Reproduction at the Cell Level
Reproduction
at the Cell Level
All living systems are ordinarily capable of reproducing themselves. The
replication of DNA, however, lies at the heart of all other forms of
reproduction. Though cell division might seem the supreme act of replication,
enzymes and other proteins are continually replicated at the ribosomes. So, too,
are membranes and mitochondria. Hence, replication is going on within a cell
whether the cell itself is dividing or not.
When cell division does occur, the parent cell splits into two daughter
cells, each of which has the same parts the parent had. In this replication
process, the two strands of each DNA molecule separate, and each daughter cell
receives a strand. Afterward, the DNA strands that the daughter cells receive
act as the templates on which their complementary strands are built. As a
consequence, the total genetic package received in part from the parent is
reestablished in each daughter cell.
In one-celled organisms cell division is the means of reproduction. In
many-celled organisms it is the means whereby the organisms' tissues grow and
are maintained. Cell division in higher organisms begins when the cell's nuclear
membrane breaks down. Then DNA's paired structures, called chromosomes, line up
in the middle of the cell and separate through a series of complex maneuvers.
Finally, a cleavage furrow forms, and the cell splits in half, providing each
daughter cell with its critical structures. Amid this spectacle, membranes are
replicated. Many of the details of replication have yet to be determined.
Biochemical
Nature of Cell Structure
Living things and their components have distinct shapes because the
architecture of their molecules is tailored for their specific tasks. For
example, each of the thousand or more protein molecules has a special job. It
might be involved in catalysis, in electron transfer, or in membrane
construction, to name a few. A protein molecule has a shape uniquely suited for
its assignment. The hemoglobin molecule, for example, has a pocket for carrying
oxygen or carbon dioxide during respiration. The rod-shaped collagen molecule
stiffens tissues and organs. The same notion of fit-to-function applies to most
other cell molecules. DNA is designed for the storage of genetic information,
phospholipids for use in membranes, and ATP for the storage of usable energy.
DNA.
Deoxyribonucleic acid, a molecule that holds the genetic information needed for
heredity.
electromechanochemical
energy. The interconversion of
electrical, mechanical, and chemical energy by the cell's energy-gathering
systems to unleash, gather, and store the power locked in ATP.
enzyme.
A protein that catalyzes, or speeds up, biochemical reactions without itself
undergoing a lasting change.
oxidation.
Loss of electrons by an atom.
phospholipid.
A bimodal molecule composed of two contradictory elements a phosphate group
attractive to water and a lipid, which repels water.
Pi.
Symbol for an inorganic phosphate.
protein.
A large molecule composed of amino acids strung together in a unique
arrangement.
reduction.
Gain of electrons by an atom.
RNA.
Ribonucleic acid, the complement to DNA,
which transcribes DNA's
genetic instructions for the manufacture of proteins.
BIOCHEMISTRY.
Scientists in the field of biochemistry study the chemical basis of
life's activities. They have shown that all living things amoebas and elephants
alike share many similarities at the level of atoms and molecules. Without
exception, all animals and plants operate on the basis of a few unvarying
biological principles. These principles are: all forms of life consist of basic
units called cells; every living thing has a heredity; all vital activities
require energy; all cells undergo certain key chemical reactions; and all living
groups reproduce. What goes on in the life of a cell stems from an interplay of
these few important principles.
The
Cell and Its Membranes
To understand cell activities one must know about membranes and their
functions. A cell is surrounded by a continuous membrane. It walls the cell's
interior from the outer environment. The life processes go on inside the
cytoplasm, or cell interior. The cell interior contains tiny organelles with
membranes. These organelles include the mitochondrion (plural, mitochondria),
the chloroplast (in plants only), the endoplasmic reticulum, and the nucleus.
All the membranes of a cell are so thin that their width can be seen only
under the extremely high magnification of the electron microscope (see
Microscope). A membrane is constructed from two types of molecules proteins and
phospholipids. They nest together to form the membrane. Both types of molecules
have two surfaces. One surface, the hydrophilic one, water. The other surface,
the hydrophobic one, water but likes oil. Membrane proteins and phospholipids
are arranged in paired tiers, with protein tiers alternating with phospholipid
tiers. Since water is a major component of the cytoplasm and also of the outside
environment, the fashion in which protein and phospholipid surfaces react to
water forms the unique basis of membranes. Arranged in paired tiers, the
membrane molecules expose their water-loving surfaces to the water both inside
and outside the cell. By contrast, their water-hating, oil-loving surfaces avoid
the water by lining up opposite each other at the middle of the membrane. This
tightly organized molecular arrangement is so stable that it tenaciously resists
disruption. Even when disrupted by strong forces, it tries to reseal any
momentary holes to keep a continuous surface. Only membrane proteins, however,
are designed for membrane service. Ordinary proteins having only water-loving
surfaces cannot be used in membranes.
Each of the cell's organelles has its own distinctive membrane containing
specific types of proteins and phospholipids. The specificity of membranes is
possible because they can contain an endless variety of water-loving and
oil-loving components as long as their bimodal character is kept.
What does a membrane do? One of its functions is to serve as a container.
Another is to act as a barrier for preventing molecules from moving into and out
of a cell at random. A membrane does this by providing molecular that regulate
which molecules can enter and which cannot. Still another function is fulfilled
by a membrane: it houses some of the cell's enzymes as well as its
energy-converting .The membrane enzymes, which are special proteins themselves,
carry out respiration needed for energy production, active transport of
materials across membranes, metabolic cycles essential for life, and many
molecule-building activities (see Biophysics; Enzymes).
Enzymes can be easily assembled on membranes. This feature pays enormous
dividends to a cell because its vital biochemical reactions are facilitated by
these important proteins. The manner in which protein molecules pair together in
the double-tier arrangement of membranes is akin to the way in which
complementary strands of deoxyribonucleic acid (DNA) pair. Since DNA, the
important molecule of heredity, directs the assembly of enzymes and other
proteins by complementarily matching certain chemical groups, it is clear why
complementarity plays such a major role in cellular activities.
DNA
Carries Heredity
Every living system has a blueprint for replication, or making copies of
itself. This blueprint is commonly called heredity. The key structure of the
hereditary process is the long, spiral DNA molecule. DNA consists of two
complementary strands coiled around each other to form a twisting ladder called
a double helix (see Genetics). The strands are made up of varying sequences of
chemical groups which are called nucleotides. A nucleotide consists of a sugar
and a phosphate group plus either of two purine bases adenine (A) and guanine
(G) or either of two pyrimidine bases thymine (T) and cytosine (C).
DNA contains the genetic code for making proteins from smaller molecules
called amino acids.
[3]
[1]Excerpted
from Compton's Reference Collection
1996. Copyright (c) 1995 Compton's NewMedia, Inc.
[2]Excerpted
from Compton's Reference Collection
1996. Copyright (c) 1995 Compton's NewMedia, Inc.
[3]Excerpted
from Compton's Reference Collection
1996. Copyright (c) 1995 Compton's NewMedia, Inc.
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